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The PRINCIPLE trial aims to find treatments for COVID-19 for older people. We want to find medicines that can help people with COVID-19 symptoms get better quickly and stop them needing to go to hospital.
The trial is open to people aged 65 or over even without other illnesses who have symptoms of COVID-19.
It is also open to those aged 50 to 64 who are experiencing symptoms that are likely to be caused by a COVID-19 infection and have at least one of the following conditions:
A known weakened immune system because of a serious illness or medication (e.g. chemotherapy);
Known heart disease or high blood pressure;
Known asthma or lung disease;
Known diabetes not treated with insulin;
Known mild hepatic impairment (liver disease);
Have previously had a stroke or have known neurological problems.
Symptoms of COVID-19:
a new, continuous cough
and/or a high temperature.
These symptoms need to have been experienced for fewer than 15 days.
The trial is recruiting participants through this website if you fit the criteria and want to know more about the study then use this link